How do I know if I am low?

A serum B12 test, available on any standard blood panel. Ask for it by name. If the result is borderline, methylmalonic acid is a more sensitive follow-up.

Methylcobalamin or cyanocobalamin?

Both raise B12 levels effectively in the great majority of people. Methylcobalamin is the active form and is often preferred on principle. Cyanocobalamin is more stable and better studied. For most people, the difference is not practically significant.

Why is my urine bright yellow?

Riboflavin, vitamin B2, which is in most B-complex products. It is harmless and it means you are excreting what you do not need.

Can I take too much B12?

B12 is water soluble with no established upper limit, and excess is excreted. It is one of the safer vitamins to oversupply. That is not a reason to take large doses of it.

ENERGY

The best energy and B12 gummies

B12 does not give you energy. It corrects a deficiency that causes fatigue. If you are not deficient, no dose will do anything, and a blood test costs less than a year of gummies.

Jump to the ranking

Last reviewed September 2026 · Next review December 2026

We earn a commission on some links, at no cost to you. It does not change our rankings. How we rank →

The short answer

Top pick: Nature Made Zero Sugar Vitamin B12 Gummies, 1,000 mcg. USP Verified, and B12 was one of the first four products USP ever verified in gummy form.
Best combination formula: Olly Daily Energy, if you want B12 alongside CoQ10.
Do this first: ask for a B12 level with your next blood panel. It is a cheap, standard test.

What we checked

We screened 21 B12 and energy gummies, checked USP and NSF status, compared the B12 form used, flagged products relying on caffeine or proprietary blends, and analyzed reviews across five retailers. Five products met our threshold. How we rank →

The honest caveat

A vitamin cannot give you energy. It can only remove a reason you do not have any.

B12 is required for red blood cell formation and nerve function, and a genuine deficiency causes profound fatigue among other things. Correcting that deficiency produces a dramatic improvement, which is where the entire "B vitamins for energy" category comes from.

But if your B12 level is normal, supplementing it does nothing detectable. The excess is water soluble and you excrete it. The bright yellow urine people notice is riboflavin doing exactly that.

Who is actually at risk of low B12: vegans and vegetarians, since B12 comes almost entirely from animal foods. People over 50, because stomach acid production declines and absorption falls with it. People taking metformin or long-term proton pump inhibitors, both of which impair absorption. People who have had gastric bypass or who have Crohn's disease or celiac disease.

If you are in one of those groups, a B12 supplement is genuinely worth taking and a gummy is a perfectly good way to take it. If you are not, and you are tired, the cause is more likely sleep, iron, thyroid, or something else that a blood test will find faster than a supplement aisle will.

Also worth naming: some products in this category are caffeine in a gummy. That is a legitimate product but it is a different one, and it should be on the front of the bottle rather than in the ingredient list.

Answer nine questions and we will tell you whether this is the right category for you.

Take the quiz →

The ranking

Our three picks, in order

Score / 100

Best overallGUMMY

Supergummies score86

Screened

Nature Made

Nature Made Zero Sugar Vitamin B12 Gummies, 1,000 mcg

USP Verified, no sugar, and descended from one of the four products USP first built gummy testing methods for.

What is in it

Active1,000 mcg vitamin B12
SugarZero, sweetened with sugar alcohols

ServingNot confirmed

VerificationUSP Verified

Cost per dayNot confirmed

Read the Nature Made brand profile →

Check price on Amazon Reviews on Trustpilot →

What people like most

USP Verified. Nature Made's Energy B12 gummy was among the first four gummy supplements USP ever verified, and USP had to build new tests for the dosage form to do it. That history is the reason the line is trusted.
Zero sugar, which matters more here than elsewhere because B12 is a supplement people take daily and indefinitely.
Reviewers who were actually low in B12 describe a substantial change, and those reviews are notably different in tone from the rest of the category.
Cheap and available everywhere, including warehouse clubs in large counts.

What people might not like

If your B12 is normal, you will feel nothing, and a large share of reviews say exactly that. It is not a flaw in the product.
Sugar alcohols cause gas or loose stools in a minority of people.
B12 alone, without the iron, D, or thyroid support that are the other common causes of fatigue.
Cyanocobalamin rather than methylcobalamin in most SKUs, which is fine for the overwhelming majority of people but a point of preference for some.

Score breakdown

Each bar shows points earned out of that component’s weight in the 100-point Supergummies Score.

Sentiment26/35

Verification25/25

Formulation16/20

Livability9/10

Value10/10

Runner-up 1GUMMY

Supergummies score77

Screened

Olly

Olly Daily Energy Gummies

B12 plus CoQ10 and goji, for people who want more than a single vitamin and understand what they are and are not getting.

What is in it

ActivesNot confirmed

Serving2 gummies

VerificationNot confirmed

FlavorTropical

Read the Olly brand profile →

Check price on Amazon Reviews on Trustpilot →

What people like most

The combination approach appeals to people who suspect their fatigue is not a single-nutrient problem.
CoQ10 is involved in cellular energy production and has better evidence in people taking statins, which is a genuinely relevant subgroup.
Taste, as with the rest of Olly's line, is the most cited reason people stay consistent.
No synthetic colors or flavors.

What people might not like

The CoQ10 dose in a gummy is well below what most CoQ10 research uses, so its presence is more meaningful on the label than in the body.
Melting and fusing in warm weather, as with every Olly product.
More expensive than a simple B12 gummy for benefits that are harder to attribute.
Reviews are more mixed than for the single-ingredient options, with a larger share reporting no effect.

Score breakdown

Each bar shows points earned out of that component’s weight in the 100-point Supergummies Score.

Sentiment27/35

Verification14/25

Formulation12/20

Livability8/10

Value7/10

Runner-up 2GUMMY

Supergummies score75

Screened

Vitafusion

Vitafusion B12 Energy Support Gummies

the widely available budget option from the brand that built the gummy vitamin category.

What is in it

ActiveVitamin B12

ServingNot confirmed

VerificationNot confirmed

FlavorBerry

Read the Vitafusion brand profile →

Check price on Amazon Reviews on Trustpilot →

What people like most

Inexpensive, and stocked essentially everywhere, which is a real advantage for something you take daily for years.
Reviewers describe it as pleasant tasting and easy to remember, and consistency is most of what matters with B12.
Vitafusion's scale means the product is rarely out of stock and rarely price-spiked.
Gluten free, and free of high fructose corn syrup and synthetic dyes.

What people might not like

USP verification applies to some vitafusion products at select retailers, not to the line as a whole, so check the specific bottle rather than trusting the brand.
Added sugar.
Same fundamental limitation: no effect if you are not deficient.
Vitafusion changed ownership in December 2025, and formulation and quality under new ownership is not yet established. Worth watching.

Score breakdown

Each bar shows points earned out of that component’s weight in the 100-point Supergummies Score.

Sentiment26/35

Verification10/25

Formulation16/20

Livability9/10

Value10/10

Compared

	Nature Made Nature Made Zero Sugar Vitamin B12 Gummies, 1,000 mcg	Olly Olly Daily Energy Gummies	Vitafusion Vitafusion B12 Energy Support Gummies
Score	86	77	75
Actives	B12, 1,000 mcg	B12, CoQ10, goji	B12
Verification	USP Verified	Not confirmed	Varies by retailer
Sugar	Zero	Added	Added
Gummies per dose	Not confirmed	2	Not confirmed

The other format

SUBLINGUAL

B12 absorption can change the format choice

For someone taking metformin or a proton-pump inhibitor, sublingual B12 avoids relying as heavily on gut absorption. It is still only the right answer when bloodwork shows a B12 problem.

How to choose

Get the blood test first.

A serum B12 level is inexpensive and routine. It converts a guess into a decision.

Check whether there is caffeine in it.

Some products in this category are caffeine with vitamins attached. That is fine if it is what you want and a problem if you take one at 4pm without realizing.

Do not buy a proprietary "energy blend."

If the label will not tell you the doses, it is because they are small.

Consider what else is on the list.

Iron deficiency, low thyroid, poor sleep, and depression all present as fatigue and all are far more common than B12 deficiency in people who eat meat. A supplement aisle is not a diagnostic tool.

If you are vegan, just take it.

B12 comes almost entirely from animal foods. This is one of the clearest cases in all of supplementation, and a gummy is a perfectly good delivery format.

Who should skip these

Anyone whose fatigue is new, severe, or accompanied by weight change, breathlessness, or low mood. That deserves a workup, not a gummy.
Anyone with Leber's hereditary optic neuropathy, for whom cyanocobalamin is contraindicated.
Anyone already taking a B-complex or multivitamin, who should check for duplication.
Anyone expecting a stimulant effect. B12 is not one, and if that is what you want, this is not it.

Questions

Only if you are deficient. In people with normal B12 levels, supplementation does not improve energy. This is the most misunderstood thing in the entire supplement market.

Hair, Skin & Nails →

Sources

USP Verified product database, quality-supplements.org
Nature Made USP verification announcement and product history
Retailer review corpus