Nature Made

The pharmacy-aisle mainstay with the deepest USP Verified record in the mass-market supplement category, owned by Otsuka Pharmaceutical through its subsidiary Pharmavite.

Founded

1971

Headquarters

Mission Hills / West Hills, Los Angeles, California

Ownership

Pharmavite, LLC, owned by Otsuka Pharmaceutical (acquired 1989) [3](https://en.wikipedia.org/wiki/Pharmavite)

Verification

USP Verified across a large share of its line; in 2002 became the first dietary supplement brand verified by the U.S. Pharmacopeia, and in 2016 the first to achieve USP verification for a gummy product [5](https://en.wikipedia.org/wiki/Nature_Made)

History

Nature Made was founded in 1971 in Los Angeles by pharmacist Barry Pressman and entrepreneur Henry Burdick under the company Pharmavite, built on the idea that basic nutritional supplementation could support long-term health [3](https://en.wikipedia.org/wiki/Pharmavite). Otsuka Pharmaceutical, a Japanese healthcare company, acquired Pharmavite in 1989 and has owned it since [3](https://en.wikipedia.org/wiki/Pharmavite).

In 2002, a Nature Made product became the first dietary supplement in the U.S. verified under the United States Pharmacopeia's Dietary Supplement Verification Program, a program that audits manufacturing facilities, confirms label-claim potency, and screens for contaminants [4](https://www.naturemade.com/pages/what-is-united-states-pharmacopeia). The brand has since built out the largest USP Verified product portfolio of any national vitamin brand, and in 2016 became the first company to achieve USP verification for a gummy supplement [5](https://en.wikipedia.org/wiki/Nature_Made).

Pharmavite has grown beyond the core Nature Made line through acquisitions, including FoodState/MegaFood in 2014 and Uqora in 2021, and has launched adjacent lines such as Equelle for menopause support and Nurish, a personalized-vitamin subscription service [3](https://en.wikipedia.org/wiki/Pharmavite).

Not every Nature Made product carries USP verification. Some lines, including its hair, skin and nails gummy, are sold without the USP mark, so verification status should be checked product by product rather than assumed brand-wide.

Why it is trusted

  • +The broadest USP Verified product lineup of any mass-market vitamin brand, in both tablet and gummy formats.
  • +More than fifty years of continuous operating history under a stable, well-documented ownership chain (Pharmavite, owned by Otsuka since 1989).
  • +Maintains a standing scientific advisory board established in 1999 to review formulation quality.

Where we would be careful

  • USP verification does not cover the entire product catalog; some individual SKUs, including some gummy lines, are not USP Verified, and shoppers should confirm the specific product rather than the brand overall.

Where Nature Made ranks

Sources

  • Pharmavite, Wikipedia: https://en.wikipedia.org/wiki/Pharmavite
  • Nature Made, Wikipedia: https://en.wikipedia.org/wiki/Nature_Made
  • Pharmavite company history: https://www.pharmavite.com/company/history/
  • What is USP & What Does USP Verified Mean?, Nature Made: https://www.naturemade.com/pages/what-is-united-states-pharmacopeia

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